A. LASAR
B. Introductory courses
C. Intermediate courses
D. Advanced courses
E. Other required courses
| A. LASAR |
Note: In Fall 2009, Queens College will move from the current LASAR system to a new system. As this new system is developed, the information in this section will change to reflect the changing general education requirements.
Students generally require an introductory chemistry course for one of two
purposes:
1. To prepare for more advanced courses in a major (e.g. chemistry,
biology, geology, etc.) or for the pre-health professional program or
2. To fulfill LASAR credits in Physical and Biological Sciences, Group A and/or Group
B.
For Chemistry, Biochemistry, Biology and Geology majors and any pre-health professional students, Chemistry 113 and 114 are the appropriate introductory sequence.
For Home Economics majors specializing in Food and Nutrition and for Biology-Education majors, the Chemistry 019/159/179 sequence is appropriate.
The following courses may be used to meet LASAR requirements in Physical
and Biological Sciences:
|
Group A (laboratory component) |
Group B |
|---|---|
|
Chem. 113 |
Chem. 114 (113 is a prerequisite) |
|
Chem. 019 |
Chem. 159 (019 is a prerequisite) |
|
Chem. 016 + 017 |
Chem. 016 |
| B. INTRODUCTORY COURSES |
| Course | Description | Credits | Lect. (Rec.) hours | Lab. hours | Prerequisites/Corequisites |
| Chemistry 016 | Chemistry in Modern Society | 3 | 3 | 0 |
Not open to students who have taken Chemistry 019 or Chemistry 113 |
| Chemistry 017 | Chemistry for the Consumer | 1 | 0 | 3 | Chemistry 016 |
| Chemistry 019** | Basic Chemistry | 4 | 2 (1) | 3 | |
| Chemistry 113* | General Chemistry I | 5 | 3 (1) | 3 | |
| Chemistry 114* | General Chemistry II | 5 | 3 (1) | 3 | Grade of C- or higher in Chemistry 113 and in Mathematics 122 or equivalent |
| Chemistry 159** | Basic Organic Chemistry | 4 | 2 (1) | 3 | Grade of C- or higher in Chemistry 019 or equivalent |
| Chemistry 179** | Basic Biochemistry | 4 | 2 (1) | 3 | Grade of C- or higher in Chemistry 159 or equivalent |
*Required course for students pursuing a major or a minor in
chemistry or biochemistry, and for all pre-health professional students.
**Required course for students pursuing a major in Food and
Nutrition.
| Chemistry 016 - Chemistry in Modern Society - Fall and Spring |
(3 lecture hours; 3 credits)
Not open to students who have taken Chemistry 019 or 113.
Meets LASAR requirements in Physical and Biological Sciences Group B or, if taken with Chemistry 017, Group A.Required for a major in Family & Consumer Sciences with a specialization in Family and Consumer Studies, in K-12 Teacher Education and in Textiles and Apparel
A survey of chemistry designed to acquaint non-scientists with aspects of chemistry of interest and concern to the average citizen. The course provides an introduction to atoms and molecules and to chemical reactions that play a significant role in modern life. Included in this treatment are discussions of important types of molecules found in living systems. Topics such as the genetic code and recombinant DNA techniques ("genetic engineering"); the role of hormones in plants, animals and insects; the nature of genetic diseases; viruses; the cancer problem and chemotherapy are among those considered. The course deals with aspects of chemical technology and chemical aspects of environmental problems. In this connection, energy resources, material resources, and the role of synthetic and analytical procedures are considered.
| Chemistry 017 - Chemistry for the Consumer - Fall and Spring |
(3 laboratory hours; 1 credit)
Prerequisite or Corequisite: Chemistry 016
Meets LASAR requirements in Physical and Biological Sciences Group A if taken with Chemistry 016.Required for a major in Family & Consumer Sciences with a specialization in Family and Consumer Studies, in K-12 Teacher Education and in Textiles and Apparel
Provides a first-hand laboratory experience of chemistry based products and processes. The emphasis of the course is to provide a basis of knowledge for the average consumer. Students prepare and/or analyze consumer products such as headache tablets and cleansers, as well as investigate the chemistry of substances such as acids and bases, and the properties of selected chemicals. Experience will be gained in glassblowing and in some aspects of qualitative analysis, such as the detection of silver, mercury and lead in water solutions by means of precipitation reactions and differences in solubilities; and also by means of paper chromatography, and quantitative analysis, such as the determination of the amount of oxygen in air.
MAT charge: $18
| Chemistry 019 - Basic Chemistry - Fall and Spring |
(2 lecture hours, 1 recitation hour, 3 laboratory hours; 4 credits per semester)
Meets LASAR requirements in Physical and Biological Sciences Group A.Required for a major in Family & Consumer Sciences with a specialization in DPD and in Food and Nutrition. Also required for a major in Nutrition and Exercise Sciences, in Physical Education, and in Biology - Education Track.
This is an introductory chemistry course that covers in one semester many of the topics also covered in the two semester general chemistry course, though in less depth. Courses of study for which this Chemistry 019 may be appropriate or required include: home economics, nursing, occupational therapy and psychology. Some of the topics discussed include: measurement and significant figures, the metric system, exponential notation, the elements and chemical compounds, atomic structure, gases, liquids, solids, chemical reactions and stoichiometry, kinetics, equilibrium, solutions, acids and bases, nuclear energy and radioactivity.
The laboratory will introduce the student to methods and measurements in science, with an emphasis on direct observation and measurement of phenomona studied in lecture.
Note: Students who need to take Chemistry 251 and 252, a full year course in organic chemistry, should not ordinarily take chemistry 019, but rather Chemistry 113 and 114.
A grade of C- or higher in this course is required as a prerequisite for the next course in the series, Chemistry 059, Survey of (Basic) Organic Chemistry.
MAT charge: $18
| Chemistry 113, 114 - General Chemistry - Fall and Spring |
(3 lecture hours, 1 recitation hour, 3 laboratory hours; 5 credits per semester)
Prerequisites: For Chemistry 114, a grade of C- or better Chemistry 113.
Meets LASAR requirements in Physical and Biological Sciences Group A (113) and Group B (114)Required for Chemistry and Biochemistry majors and minors. Also required for Majors in Geology, in Environmental Sciences-Chemistry concentration, and in Biology. Required for all pre-health professional students.
Chemistry 113 and 114 constitute the mainstream introductory course that serves as an introduction to and prerequisite for the more advanced courses. It is designed to give a thorough grounding in the basic concepts and techniques of modern chemistry. The course requires a facility in high school mathematics through algebra, but not including calculus.
The following is a partial list of topics covered in the course:
The laboratory illustrates concepts learned in lecture, furnishes a knowledge of techniques needed for more advanced work, and provides practice in data recording and report writing. The work includes, but is not confined to: gravimetric determination, titrations, qualitative analysis and experiments illustrating the principles of stoichiometry, gas laws, colligative properties, solution equilibria, thermochemistry, electrochemistry, kinetics and photochemistry.
MAT charge: $18 per semester.
| Chemistry 159 - Basic Organic Chemistry - Fall and Spring |
(2 lecture hours, 1 recitation hour, 3 laboratory hours; 4 credits per semester)
Prerequisite: A grade of C- or higher in Chemistry 019 or equivalent.
Meets LASAR requirements in Physical and Biological Sciences Group B.Required for a major in Family & Consumer Sciences with a specialization in DPD and in Food and Nutrition. Also required for a major in Nutrition and Exercise Sciences, in the Environmental Science - Chemistry concentration and in the Biology - Education Track.
This course is a one semester survey of organic chemistry. The first part of the course deals with fundamentals and the presentation concentrates on nomenclature, structure, and typical reactions of important functional groups. The aliphatic, alicyclic, and aromatic compounds are presented in an integrated format. The second part of the course concentrates on a broad treatment of carbohydrates, amino acids, proteins, some heterocyclic compounds, and macromolecules, since these constitute the essential components of living systems. The thrust of the course is on those areas of organic chemistry that are fundamental to an understanding of chemical reactions that occur in living organisms. The aim is to give the student fundamentals that will enable him or her to have a better appreciation of the role of organic chemistry in our daily lives. The course is intended for non-science majors and should be of special interest to majors in home economics, nutrition, biology-education, health-education, physical therapy and other health-related fields.
MAT charge: $25
| Chemistry 179 - Basic Biochemistry - Fall and Spring |
(2 lecture hours, 1 recitation hour, 3 laboratory hours; 4 credits per semester)
Prerequisite: A grade of C-; or higher in Chemistry 019 and 159 or equivalents.Required for a major in Family & Consumer Sciences with a specialization in DPD, for a major in Nutrition and Exercise Sciences and for a major in Environmental Science - Chemistry concentration.
This elementary biochemistry course is a study of the structure, properties, and metabolism of the major groups of compounds of biological importance, with special emphasis on the role of those compounds required in diet. In addition to presenting the chemistry of major cellular constituents, the course also covers enzymology, bioenergetics, the metabolism of carbohydrates, proteins, lipids, nucleic acids, and the important trace nutrients. Problems of metabolic regulation in relation to nutrient intake will also be discussed. The laboratory will introduce a variety of basic procedures used in biochemistry: Application of radioactive tracers; use of enzymes and their assay; chromatographic techniques; assay of proteins and vitamins. Not open to chemistry majors.
Chemistry 019, 159 and 179 constitute a three-semester sequence designed for students in science-related fields to give them a good overview of inorganic/general, organic and biochemical branches of the field of chemistry.
MAT charge: $18
| C. INTERMEDIATE COURSES |
| Course | Description | Credits | Lect. (Rec.) hours | Lab. hours | Prerequisites/Corequisites |
| Chemistry 240 | Environmental Chemistry | 3 | 3 | 0 | Grade of C- or higher in Chemistry 114 or equivalent. A grade of C- or higher in Chemistry 251 is also suggested, but not required. |
| Chemistry 241 | Quantitative Analysis | 4 | 3 | 3 |
Grade of C- or higher in Chemistry 114 or equivalent |
| Chemistry 251*,† | Organic Chemistry I | 5 | 3 (1) | 4 | Grade of C- or higher in Chemistry 114 or equivalent |
| Chemistry 252*,† | Organic Chemistry II | 5 | 3 (1) | 4 | Grade of C- or higher in Chemistry 251 or equivalent |
| Chemistry 291 | Introduction to Research in Chemistry and Biochemistry | 1 - 3 | 0 | 3 - 9 | Grade of C- or higher in Chemistry 113 and by permission of the Department |
| Chemistry 313* | Physical Chemistry I | 3 | 3 | 0 | Grade of C- or higher in Physics 146 (or 122), in Mathematics 143 (or 152) and in Chemistry 114 |
| Chemistry 331* | Advanced Inorganic Chemistry | 3 | 3 | 0 | Grade of C- or higher in Chemistry 252 |
| Chemistry 371* | Biochemistry I | 4 | 4 | 0 | Grade of C- or higher in Chemistry 252 and in Biology 108 |
*Required course for students pursuing a major in chemistry or
biochemistry.
†Required for pre-health professional
students.
| Chemistry 240 - Environmental Chemistry - Fall |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 114 or equivalent.
A grade of C- or higher in Chemistry 251 is also suggested (but not required).Required for the Environmental Science - Chemistry concentration major.
The chemistry of our environment, with an emphasis on New York City, which has some of the largest environmental problems and some exemplary solutions. Areas and topics covered may include: Air: atmospheric structure and composition, the Greenhouse Effect and its enhancement, stratospheric ozone depletion by CFCs, temperature inversions and air quality, criteria air pollutants (CO, particulate matter, photochemical oxidants, smogs, SO2 ), indoor air pollution, formaldehyde, radon, asbestos; introduction to toxicology; the Clean Air Act; automobiles: internal combustion engine, gasoline and additives (lead, oxygen), emissions and control, diesels. Acid deposition and its effects. Water: chemistry of natural water systems, nutrients and eutrophication; drinking water quality, Safe Drinking Water Act, water treatment, THMs, the New York City water supply system; sewage and sewage treatment, NYC's sewage system and sludge disposal; the Clean Water Act; Municipal solid waste, landfills, incineration, dioxins, New York City's landfill at Fresh Kills, recycling, resource recovery; Hazardous wastes. Agricultural chemicals: fertilizers, pesticides, DDT as a classic case, alternatives to chemical pesticides, semiochemicals. Heavy metals: lead, mercury, cadmium, arsenic: uses, exposure routes, toxicity, therapy, control. Soil chemistry. Food and food additives.
| Chemistry 241 - Quantitative Analysis |
(3 lecture hours; 3 laboratory hours; 4 credits)
Prerequisites: A grade of C- or higher in Chemistry 114 or equivalent.
The primary emphasis in quantitative analysis is on the principles of chemical analysis and on laboratory technique. After a review of stoichiometry, and an introduction to volumetric analysis and the treatment of analytical data, theories of acids and bases are discussed. Following an introduction to the concept of activity, pH calculations are applied in some detail to titrations involving various combinations of strong and weak, mono- and poly-protic, acids and bases. The theory of indicators is considered.
Oxidation-reduction equilibria are studied in terms of the accepted conventions regarding electrode potentials and electrochemical cell reactions. The Nernst equation provides the basis for analytical application of the redox equilibria. Reference electrodes are discussed, and titrations curves are calculated for several different types of electrochemical titration reactions.
After an introduction to complex ion and chelate chemistry in solution, the theory and application of ethylenediamine tetraacetic acid titrations is treated in some detail.
Several types of potentiometric titration are considered and various types of ion-selective electrodes are surveyed. Other electroanalytical methods are described, including recently introduced microelectrodes and modified electrodes.
Quantitative spectrophotometry, another important analytical technique, is studied in some detail on the basis of Beer's Law.
Analytical separations by solvent extraction, chemical precipitation, and several types of chromatography (thin-layer, ion-exchange, and gas) are subjects of the final quarter of the lectures. The quartz crystal microbalance is discussed.
The laboratory consists of a series of experiments, including conventional determinations as well as more modern analyses. Exact quantitative determinations of several different types of samples are carried out using pH, potentiometric, and chelometric titrations; spectrophotometry; and gas chromatography. Ion-exchange is used in the analysis of other samples.
MAT charge: $18
| Chemistry 251, 252 - Organic Chemistry I and II - Fall and Spring |
(3 lecture hours; 1 recitation hour; 4 laboratory hours; 5 credits each semester)
Prerequisites: For Chemistry 251, a grade of C- or higher in Chemistry 114; for Chemistry 252, a grade of C- or higher in Chemistry 251.Required for all chemistry and biochemistry majors and minors. Required for all pre-health professional students.
Chemistry 251, 252 is a two semester college level course in organic chemistry that meets the requirements for students pursuing careers in chemistry, biology, medicine, dentistry, veterinary medicine, pharmacy, pharmacology, etc.
The course attempts to correlate structure and reactivity. It begins with an introduction to bonding and properties of molecules. Reaction mechanisms and theory are introduced early and used throughout the course. The aliphatic compounds are considered first. Eventually, aliphatic and aromatic compounds are presented in an integrated way. Considerable emphasis is placed on basic theory. Stereochemistry, conformational analysis, and spectroscopy are integrated into the discussion of the preparation and properties of each of the major classes of organic compounds. In addition to standard classes of compounds, such topics as organometallic chemistry, carbohydrates, amino acids, terpenes, heterocycles, and polymers are given varying degrees of attention.
In the laboratory portion of the course, the student becomes familiar with basic experimental techniques of organic chemistry. Such common operations as distillation, crystallization, boiling point and melting point determination, chromatography, and extraction are introduced. Experiments are performed that deal with the preparaton and purification of representative groups of compounds. Qualitative analytical procedures are introduced to characterize and prepare derivatives of various classes of compounds.
MAT charge: $25 per semester
| Chemistry 291 - Introduction to Research in Chemistry and Biochemistry - Fall and Spring |
(3 laboratory hours; 1 credit)
Prerequisites: A grade of C- or higher in Chemistry 113 and by permission of the Department.
Introduction to research techniques in chemistry and biochemistry under the
supervision of a member of the department. The purpose of this course is
to effect a transition from experiments for which the outcome is known to
designing and doing experiments to secure the information necessary to solve a
problem for which the outcome is not known.
MAT charge: $30 per semester
| Chemistry 313 - Physical Chemistry I: Chemical Thermodynamics - Fall |
(3 lecture hours; 3 credits)
Prerequisites: Chemistry 114, Physics 146 (highly recommended) or 122, and Mathematics 143 or 152 with a grade of C or higherRequired for all chemistry and biochemistry majors.
This course is an introduction to chemical thermodynamics and certain of its applications. The definition of ensembles and distribution functions lead to the derivations of temperature, the first law of thermodynamics, definitions of heat and work, the Joule effect. The second law, the Carnot cycle and the Clausius inequality; entropy creation as the sole criterion of spontaneous change. Systems in contact with a heat reservoir: the Gibbs and Helmholtz functions. The Gibbs equations; Maxwell relations. The Joule-Kelvin effect. The third law and measurement of compositional entropy changes. The Gibbs equations for systems of variable composition; partial molar properties; the chemical potential. The thermodynamic basis of thermochemistry: effects of compositional change. Gas-phase chemical equilibrium. Heterogeneous equilibrium: the Clapeyron equation; the phase rule and phase maps. The thermodynamics of binary solutions: ideal and ideally dilute models, colligative properties, activity; chemical equilibrium in solutions
| Chemistry 331 - Advanced Inorganic Chemistry - Fall |
(3 lecture hours; 3 credits)
Prerequisites: A grade of C- or higher in Chemistry 251.Required for all chemistry and biochemistry majors.
This course is designed to enlarge the student's knowledge of descriptive inorganic chemistry and to acquaint the student with various theoretical approaches to the structure and behavior of inorganic compounds. In accomplishing the latter objective the course draws on concepts learned in physical chemistry but in a largely qualitative way.
The course begins with a review of electronic structure of atoms and goes on to consider structure and bonding in covalent molecules, coordination compounds and ionic substances. An introduction to the application of symmetry, including Group Theory, is included. Additional topics include acids and bases, chemistry in non-aqueous solvents, kinetics, electrochemistry, magnetism, spectroscopy, catalysis and bio-inorganic chemistry. Descriptive topics have included boranes, organometallic compounds, noble gas compounds and interhalogen compounds.
| Chemistry 371 - Biochemistry I - Fall and Spring |
(4 lecture hours; 4 credits)
Prerequisite: A grade of C- or higher in Chemistry 252; a grade of C- or higher in Biology 108; or permission of instructor.Required for all chemistry and biochemistry majors.
This course introduces the student to the core of modern biochemistry. An introduction to amino acid and protein chemistry provides a foundation for a discussion of enzyme structure, function, and kinetics. Emphasis is placed on the organization of enzyme-catalyzed reactions into coordinated and regulated metabolic sequences. Where appropriate, specific enzyme mechanisms are discussed in relation to substrates and coenzymes. The course also examines the interaction between lipids and proteins to form biological membranes and the roles that biological membranes play in cells. Special emphasis is placed on the role of biological membranes in bioenergetics. The course also examines carbohydrate and lipid metabolism and hormonal regulation of these processes. Specific metabolic pathways and topics described include the glycolytic pathway, the gluconeogenic pathway, the pentose phosphate pathway, glycogen formation and degradation, the citric acid cycle, the respiratory chain, oxidative phosphorylation, photosynthesis, and fatty acid and triacylglycerol formation and degradation. Throughout the discussion of enzymes and metabolism consideration is given to cytological and thermodynamic aspects and to the introduction of major experimental techniques.
| D. ADVANCED COURSES |
*Required for Chemistry majors.
**Required for Biochemistry majors.
| Chemistry 314 - Physical Chemistry II: Quantum Mechanics and Spectroscopy - Spring |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 313 and in Mathematics 231.Required for all chemistry majors.
The course is devoted to the elements of quantum mechanics and the modern concepts of atomic and molecular structure and spectroscopy. Topics include the Bohr atom, de Broglie's hypothesis, the uncertainty principle, electron spin and the Pauli principle. Wave mechanics, based upon the Schrödinger equation, is introduced and applied to the particle-in-a-box, harmonic oscillator, and the hydrogen atom. The Born Oppenheimer approximation is introduced and used in the discussion of molecular orbital theory and valence bond theory. Group theory and its applications to molecular systems are introduced and then applied in the study of infrared and electronic states. Spectroscopy and photochemistry are discussed in conjunction with atomic and molecular structure. Finally, quantum statistical mechanics is introduced.
| Chemistry 315 - Physical Inorganic Laboratory I - Fall |
(1 recitation hour; 4 laboratory hours; 2 credits each semester)
Prerequisites or Corequisites: Chemistry 313Required for all chemistry and biochemistry majors.
Chemistry 315 is an advanced laboratory that studies the synthesis and characterization of inorganic compounds. This laboratory focuses on the use of physical methods to study inorganic compounds. Experiments include viscosity, bomb calorimetry and x-ray diffraction.
MAT charge: $30 per semester
| Chemistry 316W - Physical Chemistry Laboratory - Spring |
(1 recitation hour; 4 laboratory hours; 2 credits each semester)
Prerequisites or Corequisites: Chemistry 314Required for all chemistry majors.
This course is an advanced writing intensive laboratory that focuses on a study of kinetics and spectroscopy. Experiments include a detailed study of the Belosouv-Zhabotinsky reaction, keto-enol tautomerization, isomerization, nuclear magnetic resonance, room temperature and ultra-cold fluorescence and phosphorescence, and UV/Visible absorption spectroscopy.
MAT charge: $30 per semester
| Chemistry 342 - Instrumental Analysis - Spring |
(2 lecture hours; 6 laboratory hours; 4 credits)
Prerequisite or Corequisite: Chemistry 313 and 315.Required for all chemistry majors. Counts as an advanced laboratory requirement for the biochemistry major.
The laboratory offers an opportunity to gain a working acquaintance with modern instrumentation for chromatography and spectrophotometry that graduates will use in industrial labs or graduate school. Experiments are designed to study fundamental variables and applications of gas chromatography, HPLC, GC/MS, atomic absorption spectroscopy (flame and graphite furnace), FTIR, UV-vis, fluorescence, ion-selective electrodes, and coulometry. The lectures cover fundamentals of these instrumental methods plus additional techniques and topics including sampling, luminescence methods, ATR-IR, NIR and NDIR, Laser-Raman spectroscopy, mass spectrometry, ICP-AES, voltammetry, ion-exchange, and size exclusion chromatography.
MAT charge: $25
| Chemistry 354 - Advanced Organic Chemistry - Fall |
(2 lecture hours; 1 recitation hour; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 252 and 365;
Prerequisite or Corequisite: Chemistry 362.Counts as an advanced chemistry elective for the chemistry major.
An advanced course dealing with physical aspects of organic chemistry. Consideration is given to the following areas: chemical bonding, stereochemistry, principles of reaction mechanisms, structure and reactivity relationships, various reactive intermediatessuch as free radicals, ion radicals, carbenes, excited states, and a consideration of orbital symmetry as it relates to organic chemistry.
| Chemistry 363 - Selected Topics in Advanced Physical Chemistry - Fall and Spring |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 314 or by permission of the instructor.Counts as an advanced chemistry elective for the chemistry major.
This course will be on one of the following topics: (i) Introductory Quantum Chemistry, (ii) Chemical Thermodynamics, (iii) Computational Chemistry, (iv) Nanomaterials or Advanced Mass Spectrometry. These topics will rotate on a two year basis with Chemical Thermodynamics and Computational Chemistry being offered in the Spring semesters and Quantum Chemistry and Nanomaterials/Mass Spectrometry in the Fall semesters.
| Chemistry 372 - Biochemistry II - Spring |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 371.Required for all biochemistry majors. Counts as an advanced chemistry elective for the chemistry major.
This course continues the discussion of metabolism started in Chemistry 371 with an examination of phosphoglyceride, sphingolipid, sterol, and amino acid metabolism. Where appropriate, specific inborn errors of metabolism will be related to enzyme defects. The course also examines the flow of information from nucleic acids to proteins with special emphasis placed on nucleic acid structure and function, DNA replication, repair, and recombination, RNA synthesis, and protein synthesis. Special emphasis is placed on the regulation of genes. Special consideration is also given to recombinant DNA techniques such as sequencing DNA, the polymerase chain reaction, and cloning.
| Chemistry - 376 Biochemistry Laboratory - Fall and Spring |
(4 laboratory hours; 1 recitation hour; 2 credits)
Prerequisite: A grade of C- or higher in Chemistry 371.Required for all biochemistry majors. Counts as an advanced laboratory requirement for the chemistry major.
This course provides the student with training in important experimental procedures routinely used in modern Biochemistry laboratories. Emphasis is placed on written reports in which students are encouraged to evaluate their data in a critical manner that takes into account material presented in the Biochemistry lecture course (Chemistry 371). The experimental procedures taught in this course include: enzyme kinetics, protein purification by affinity chromatography, molecular weight determination of a protein by molecular sieve chromatography, handling of radionuclides, and analysis of DNA by restriction endonuclease digestion. This course also features a 2-week tutorial in the analysis of protein structure by use of molecular modeling software on a Macintosh computer.
MAT charge: $25
| Chemistry 378 - Physical Biochemistry - Spring |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 313.
Prerequisite or corequisite: Chemistry 371Required for all biochemistry majors. Counts as an advanced chemistry elective for the chemistry major.
Structure and conformation of proteins, nucleic acids, and other biopolymers; physical techniques for study of macromolecules and biological membranes; behavior and properties of biopolymers. Among the topics discussed are theoretical and applied aspects of the following: (a) Spectroscopic studies (absorption, fluorescence, magnetic resonance, infrared and Raman, circular dichroism) and calorimetry; (b) size, shape and molecular weight methods (sedimentation, diffusion, viscosity, osmometry, and light scattering. (c) kinetics and equilibria; (d) diffraction methods (X-ray and neutron). Specific examples of contributions of biophysical measurements to our understanding of the structures and functions of macromolecules will be examined.
| Chemistry 379 - Physical Biochemistry Laboratory - Spring |
(4 laboratory hours; 1 recitation hour; 2 credits)
Prerequisite: A grade of C- or higher in Chemistry 313 and 315.
Prerequisite or corequisite: Chemistry 378Required for all biochemistry majors. Counts as an advanced laboratory requirement for the chemistry major.
Application of physical chemical techniques to the study of biomolecular properties, including molecular conformations, kinetics and thermodynamic aspects of ligand binding, redox properties and separation techniques. Various spectroscopic techniques are used to investigate these phenomona, including ultraviolet-visible spectrophotometry, fluorescence spectroscopy and circular dichroism spectroscopy.
MAT charge: $25
| Chemistry 380 - Selected Topics in Biochemistry |
(3 lecture hours; 3 credits)
Prerequisite: A grade of C- or higher in Chemistry 372 or permission of instructor.
In-depth treatment of topics such as recombinant DNA technology, biochemistry of cancer, membrane structure and function, control and regulation in metabolic processes, or bioinorganic chemistry.
| Chemistry 381 - Seminar - Fall and Spring |
(2 hours; 2 credits)
Prerequisite: Permission of the Department.
Topics for each semester vary according to the Departmental Seminar schedule. Offered primarily for seniors.
| Chemistry 386 - Physical Methods of Structure Determination |
(3 lecture hours; 3 credits)
Prerequisite: Chemistry 252.Counts as an advanced chemistry elective for the chemistry major.
A survey of the main methods for determining the structures of compounds from physical measurements. Interpretation of data from infrared, mass, and nuclear magnetic resonance spectroscopy, including the use of two-dimensional techniques. Discussion of other physical methods such as x-ray diffraction and visible-ultraviolet spectroscopy.
| Chemistry 387 - Advanced Integrated Laboratory and Introduction to Research Techniques |
(1 recitation hour; 5 laboratory hours; 3 credits)
Prerequisite: Chemistry 331, Chemistry 386, and either Chemistry 314 or Chemistry 378.Counts as an advanced laboratory requirement for both the chemistry and biochemistry majors.
The synthesis, separation, and characterization of both inorganic and organic substances using advanced laboratory techniques such as syringe procedures for working in air-free systems, vacumn distillation and sublimation, use of liquid ammonia, chromatographic techniques of separation, and soxhlet extraction. Hands-on use of Fourier transform infrared and nuclear magnetic resonance spectrometers, and use of circular dichroism and fluorescence equipment.
| Chemistry 391 - Research in Chemistry an Biochemistry - Fall and Spring |
(3-9 hours to be arranged; 1-3 credits)
Prerequisite: A grade of C- or better in Chemistry 252 and permission of the department.Counts as an advanced laboratory requirement for both the chemistry and biochemistry majors.
This offering is not of the usual classroom type. It permits a student to undertake a minor research problem under the direction of a faculty member in the department. The purpose is to effect the transition from experiments for which the outcome is known to designing and doing experiments in order to secure the information necessary to solve a problem.
Admission to Chemistry 391 is by permission of the Chairman or a designated advisor on the basis of the student's previous work and the belief of the advisor and at least one instructor that the student can profit from the research experience. Once permission is secured, the student talks with several faculty members about their research interests and possible research problems. By mutual agreement of the student and faculty member, the student becomes part of an ongoing research group. In this course, the time and duration of the work is arranged with the supervising faculty member. In general there is not the usual correlation of scheduled "laboratory hours" and credits; rather the student will find that research demands a continued ongoing effort. Reports are written on the work performed and are judged by the faculty. A written report will be submitted to and approved by the Department.
This work is done in addition to other advanced coursework in the department; generally one or more appropriate advanced courses in Chemistry and/or Biochemistry should be taken along with undergraduate research.
MAT charge: $25
| E. Other Required or Suggested Courses |
| Course | Description | Credits | Lect. (Rec.) hours | Lab. hours | Prerequisites/Corequisites |
| Biology 108 | General Biology: Physiology and Cell Biology | 4 | 3 | 3 | Chemistry 113 |
| Biology 262 | Laboratory Techniques in Molecular Biology | 3 | (2) | 3 |
Grade of C- or higher in Biology 108 and in Chemistry 114 or Chemistry 159 or the equivalent. Biology 285 is strongly recommended as a prerequisite or corequisite. |
| Biology 285 | Principles of Genetics | 4 | 3 (1) | 0 | Grade of C- or higher in Biology 108 and in Chemistry 114 or Chemistry 159 or the equivalent |
| Mathematics 141 | Calculus/Differentiation | 3 | 3 | 0 | Grade of C- or higher in Mathematics 122 or placement by departmental exam or permission of the department |
| Mathematics 142 | Calculus/Integration | 3 | 3 | 0 | Grade of C- or higher in Mathematics 141 |
| Mathematics 143 | Calculus/Infinite Series | 3 | 3 | 0 | Grade of C- or higher in Mathematics 142 |
| Mathematics 151 | Calculus/Differentiation & Integration | 4 | 4 | 0 | Grade of C- or higher in Mathematics 122 or placement by departmental exam or permission of the department |
| Mathematics 152 | Calculus/Integration & Infinite Series | 4 | 4 | 0 | Grade of C- or higher in Mathematics 151 |
| Mathematics 201 | Calculus | 4 | 4 | 0 | Grade of C- or higher in Mathematics 143 or Mathematics 152 |
| Mathematics 231 | Linear Algebra I | 4 | 4 | 0 | One semester of calculus |
| Physics 121 | General Physics I | 4 | 4 | 2 | Trigonometry and algebra |
| Physics 122 | General Physics II | 4 | 4 | 2 | Grade of C- or higher in Physics 121 |
| Physics 145 | College Physics I | 4 | 4 | 2 | Grade of C- or higher in Mathematics 141 or Mathematics 151 |
| Physics 146 | College Physics II | 4 | 4 | 2 | Grade of C- or higher in Mathematics 142 or Mathematics 152 and in Physics 145 or Physics 121 |
| Biology 108 - General Biology: Physiology and Cell Biology - Fall and Spring |
(3 lecture hours, 3 laboratory hours, 4 credits)
Prerequisite: High school biology and chemistry
Prerequisite/corequisite: Chemistry 113Required for all chemistry and biochemistry majors.
Topics include the principles of cell biology, physiology, development and molecular genetics.
MAT charge: $45
| Biology 262 - Laboratory Techniques in Molecular Biology - Fall |
(2 recitation hours, 3 laboratory hours, 3 credits)
Prerequisite: A grade of C- or higher in Biology 108 and in Chemistry 114 or Chemistry 159 or equivalent
Strongly recommended prerequisite/corequisite: Biology 285Counts as an advanced laboratory elective in the biochemistry major.
Introduction to the basic laboratory techniques of molecular biology.
MAT charge: $50
| Biology 285 - Principles of Genetics - Fall |
(3 lecture hours, 1 recitation hour, 4 credits)
Prerequisite: A grade of C- or higher in Biology 108 and in Chemistry 114 or Chemistry 159 or equivalent
The inheritance, structure and function of genetic material.
| Mathematics 141, 142, and 143 - Calculus/Differentiation, Integration and Infinite Sums - Fall and Spring |
(3 lecture hours, 3 credits)
Prerequisites for 141: A grade of C- or higher in Mathematics 122 or placement by departmental exam or permission of the department.
Prerequisites for 142: A grade of C- or higher in Mathematics 141
Prerequisites for 143: A grade of C- or higher in Mathematics 142Mathematics 141, 142, and 143 or Mathematics 151 and 152 are required for all chemistry and biochemistry majors.
A three semester calculus sequence covering sets, inequalities, straight lines, circles, functions, limits, continuity, the derivative, formulas of differentiation, implicit differentiation, velocity, acceleration, maxima and minima, Rolle's theorem, the mean value theorem, points of inflection, curve sketching, antiderivatives, definite integrals, applications of the definite integral, the differentiation of logarithmic, exponential, and inverse trigonometric functions, integration, indeterminate forms, improper integrals, infinite series and expansions of functions. Applications to problems of geometry and physics.
| Mathematics 151 and 152 - Calculus/Differentiation, Integration and Infinite Sums - Fall and Spring |
(4 lecture hours, 4 credits)
Prerequisites for 151: A grade of C- or higher in Mathematics 122 or placement by departmental exam or permission of the department.
Prerequisites for 152: A grade of C- or higher in Mathematics 151Mathematics 141, 142, and 143 or Mathematics 151 and 152 are required for all chemistry and biochemistry majors.
A two semester calculus sequence covering sets, inequalities, straight lines, circles, functions, limits, continuity, the derivative, formulas of differentiation, implicit differentiation, velocity, acceleration, maxima and minima, Rolle's theorem, the mean value theorem, points of inflection, curve sketching, antiderivatives, definite integrals, applications of the definite integral, the differentiation of logarithmic, exponential, and inverse trigonometric functions, integration, indeterminate forms, improper integrals, infinite series and expansions of functions. Applications to problems of geometry and physics.
| Mathematics 201 - Calculus - Fall and Spring |
(4 lecture hours, 4 credits)
Prerequisites: A grade of C- or higher in Mathematics 143 or in Mathematics 152.Recommended for students interested in Graduate School in chemistry or in chemical engineering.
Topics include polar coordinates, vectors, solid analytic geometry, vector-valued functions, double and triple integrals, functions of several variables, partial derivatives. Wherever possible, applications are made to problems of geometry and physics.
| Mathematics 231 - Linear Algebra I - Fall and Spring |
(4 lecture hours, 4 credits)
Prerequisites: One semester of calculus.Required for all chemistry majors.
An introduction to linear algebra with emphasis on techniques and applications. Topics to be covered include solutions of systems of linear equations, vector spaces, bases and dimension, linear transformations, matrix algebra, determinants, eigenvalues, and inner products.
| Physics 121, 122 - General Physics - Fall and Spring |
(4 lecture and recitation hours, 2 laboratory hours, 4 credit hours)
Prerequisites for 121: Trigonometry and algebra.
Prerequisites for 122: A grade of C- or higher in Physics 121Physics 121 and 122 or Physics 145 and 146 are required for all chemistry and biochemistry majors. This sequence is not recommended for students in the chemistry or biochemistry major.
A non-calculus based course primarily for major sin life sciences, pre-health professions and liberal arts. Physics 121 covers mechanics, thermodynamics, kinetic theory and sound. Physics 122 covers electricity and magnetisms, geometrical and physical optics and an introduction to modern physics.
| Physics 145, 146 - College Physics - Fall and Spring |
(4 lecture and recitation hours, 2 laboratory hours, 4 credit hours)
Prerequisites for 145: A grade of C- or higher in Mathematics 141 or Mathematics 151.
Prerequisites for 146: A grade of C- or higher in Mathematics 142 or Mathematics 152 and in Physics 145 or Physics 121.Physics 121 and 122 or Physics 145 and 146 are required for all chemistry and biochemistry majors. This calculus based sequence is strongly recommended for all majors in chemistry and biochemistry.
A calculus based course intended for students who plan to study the physical sciences or engineering. Physics 145 covers the fundamental principles and laws of mechanics, thermodynamics, kinetic molecular theory and sound. Physics 146 covers electricity, magnetism and optics.
Last Modified April 23, 2006.