Home Page of Dr. Yu Chen

Assistant Professor of Organic Chemistry

Office:  Remsen 206F    Tel: 718-997-4132
Lab:     Remsen 251       Tel: 718-570-0412

 
email: yu.chen1@qc.cuny.edu

Department of Chemistry and Biochemistry
65-30 Kissena Blvd.,
Flushing, NY 11367

Research Interests:

Professor Yu Chen started his independent career at Queens College — CUNY in August 2009 after finishing his PhD work at University of Toronto with Professor Andrei Yudin and postdoctoral research work at Iowa State University with Professor Richard Larock.  Dr. Chen’s research interest includes the topics of late-transition-metal catalysis, asymmetric synthesis and catalysis, and heterocyclic chemistry.  The late-transition-metal catalysis topic plays a significant role in Chen research group.  His group is particularly interested in group 9 to 11 transition metals, especially Rh, Pd, Pt and Au.  Developing new efficient chemical transformations using these late-transition-metal catalysts is currently one of the group’s major objectives.  The late-transition-metal catalyzed asymmetric synthesis is another important research topic in Chen group.  The group focuses on designing and preparing new enantiomerically pure biaryl ligands for efficient and highly stereoselective chemical reactions catalyzed by late-transition-metals.  The synthetic methodologies developed in Chen group will be employed as the key steps in the synthesis of biologically interesting and pharmaceutically important molecules. 

Recent Publications

Chen, Y.; Markina, N. A.; Larock, R. C. “An Efficient, Microwave-Assisted, One-Pot Synthesis of Indoles Under Sonogashira Conditions,” Tetrahedron, 2009, 65, 8908-8915.

Chen, Y.; Cho, C.-H.; Shi, F.; Larock, R. C. “Synthesis of 3-Sulfenyl- and 3-Selenylindoles by the Palladium-Catalyzed Coupling of N,N-Dialkyl-2-iodoanilines and Terminal Alkynes, Followed by n-Bu₄NI-Induced Electrophilic Cyclization with Aryl Sulfenyl/Selenyl Chlorides,” J. Org. Chem. 2009, 74, 6802-6811.

Chen, Y.; Larock, R. C. “Arylation Reactions Involving the Formation of Arynes,” Chapter in Modern Arylation Methods, Ed.: L. Ackermann, J. Wiley/VCH, New York, 2009, Chapter 12, 401-473.

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Feel free to email me if you need information about my research interests and publications.