Non-Opioid Analgesic Responses
In addition to the ability of opiate drugs, opioid peptides and opioid analogues to elicit analgesic responses, our laboratory has examined the analgesic effects of other peptide systems, notably vasopressin.
Related Publications of the Bodnar Laboratory:
Bodnar, RJ, SE Karpiak, PE Mann, H Tamir, M Wilchek and BC Yoburn. Analgesic properties of a systemically-administered synthetic dipeptide of 5-hydroxytryptophan. Peptides 7: 995-999, 1986.
Bodnar, RJ, LS Truesdell, J Haldar, IA Aral, JH Kordower and G Nilaver. Elimination of vasopressin analgesia following lesions placed in the rat hypothalamic paraventricular nucleus. Peptides 7: 711-717, 1986.
Bodnar, RJ, LS Truesdell and G Nilaver. Potentiation of vasopressin analgesia in rats treated neonatally with monosodium glutamate. Peptides 6: 621-626, 1985.
Badillo-Martinez, D, N Nicotera and RJ Bodnar. Onset of pain threshold changes induced by neonatal monosodium glutamate. Int. J. Neurosci. 24: 275-279, 1984.
Kordower, JH and RJ Bodnar. Vasopressin analgesia: specificity of action and non-opioid effects. Peptides 5: 747-756, 1984.
Bodnar, RJ, MM Wallace, G Nilaver and EA Zimmerman. The effects of centrally administered antisera to neurotensin and related peptides upon nociception and related behaviors. Ann. N.Y. Acad. Sci. 400: 244-258, 1982.
Bodnar, RJ, MM Wallace, JH Kordower, G Nilaver, J Cort and EA Zimmerman. Modulation of nociceptive thresholds by vasopressin in the Brattleboro and normal rat. Ann. N.Y. Acad. Sci. 394: 735-739, 1982.
Kordower, JH, V Sikorszky and RJ Bodnar. Central antinociceptive effects of lysine vasopressin and an analogue. Peptides 3: 613-617, 1982.
Bodnar, RJ, DA Simone, DD Kelly, M Brutus, M Glusman and R Meibach. Time-dependent and dose-dependent effects of fenfluramine upon pain thresholds. Bull. Psychonom. Soc. 19: 355-358, 1982.
Bodnar, RJ and N Nicotera. Neuroleptic and analgesic interactions upon pain and activity measures. Pharmacol. Biochem. Behav. 16: 411-416, 1982.
Tamir, H, SE Karpiak, IJ Wajda, M Wilchek and RJ Bodnar. N-acetyl-5HTP-5HTP amide affects pain thresholds and brain serotonin levels. Life Sci. 25: 655-664, 1979.
Bodnar, RJ, RF Ackermann, DD Kelly and M Glusman. Elevations in nociceptive thresholds following locus coeruleus lesions. Brain Res. Bull. 3: 125-130, 1978.