|| Associate Professor
||University of Massachusetts Amherst
||D-314 Science Building
American Psychological Association
American Association for Geriatric Psychiatry
Adjunct Assistant Professor of Medical Psychology (in Psychiatry)
Columbia University and the New York State Psychiatric Institute
Department of Psychiatry
Divisions of Geriatric Psychiatry and Epidemiology
The primary research focus of my lab is on understanding and treating late-life depression, with a particular emphasis on a subtype of depression called vascular depression. In particular, we have been focusing on developing a psychometric framework for evaluating diagnostic entities in order to develop empirically-based diagnostic criteria for the disorder. As part of this effort, we are conducting an 8-week clinical trial examining the neurocognitive and neuroimaging (MRI) mediators of antidepressant treatment response (i.e., Lexapro) in patients with and without vascular depression. This study is being conducted in collaboration with the Mid and Late-Life Depression Research Clinic at Columbia University and the New York State Psychiatric Institute, as well as in the Outpatient Psychiatry and Geropsychiatry Services at Harlem Hospital. We are also interested in the role of executive dysfunction plays in late-life depression. We are extending this research in order to characterize the course of vascular depression and its relationship to other late-life psychiatric disorders such as dementia. We are also interested in understanding the nature of the executive functions, the role executive dysfunction plays in late-life depression and its relationship to dementia, and the impact of executive dysfunction on antidepressant treatment response in depressed older adults.
Sneed, J. R., Balestri, M., & Belfi, B. (2003). The use of Dialectical Behavior Therapy strategies in the psychiatric emergency room. Psychotherapy: Theory, Research, Practice, Training, 40, 265-277.
Sneed, J. R., Johnson, J. G., Cohen, P., Gilligan, C., Chen, H. Crawford, T., & Kasen. S. (2006) Gender differences in the age-changing relationship between family contact and instrumentality in emerging adulthood. Developmental Psychology, 42, 787-797.
Sneed, J. R., Roose, S. P., Keilp, J. G., Krishnan, K. R. R., Alexopoulos, G., Sackeim, H. A. (2007). Response inhibition predicts poor antidepressant treatment response in the very old depressed. American Journal of Geriatric Psychiatry, 15, 553-563.
Sneed, J. R., Rutherford, B. R., Rindskopf, D., Lane, D. T., Sackeim, H. A., & Roose, S. P. (2008). Design Makes a Difference: A Meta-Analysis of Antidepressant Response Rates in Placebo-Controlled versus Comparator Trials in Late-Life Depression. American Journal of Geriatric Psychiatry, 16, 65-73.
Rindskopf, D., & Sneed, J. R. (2008). Turning points in family contact during emerging adulthood. In: P. Cohen and R. Prouzek (Ed.), Applied Data Analytic Techniques for Turning Points Research. NJ: Lawrence Erlbaum Press.
Sneed, J.R., Keilp, J. G., Brickman, A. M., & Roose, S. P. (2008). The Specificity of Neuropsychological Impairment in Predicting Antidepressant Non-Response in the Very Old Depressed. International Journal of Geriatric Psychiatry, 23, 319-323.
Sneed, J. R., & Whitbourne, S. K., & Culang, M. (2008). Trust, Identity, and Ego Integrity: Modeling Erikson’s Core Stages over Thirty-Four Years. Journal of Adult Development, 13, 148-157.
Sneed, J. R., Rindskopf, D., Steffens, D. C., Krishnan, R. R., Roose, S. P. (2008). The vascular depression subtype: Evidence of internal validity. Biological Psychiatry, 64, 491-497.