SUSAN CROLL

Title	Associate Professor
Area	Neuropsychology
Ph.D.	City University of New York, 1994
Office	215 Razran
E-mail	susan.croll@qc.cuny.edu
Office Phone	718-997-3551

Professional Activities:

Society Memberships:
    The Society for Neuroscience
    The Association for Psychological Science
    New York Academy of Sciences
    Sigma Xi (Chapter President)
    Psi Chi

Ad Hoc Reviewer, National Institutes of Health
Scientific Review Board, CURE Foundation (Citizens United to Cure Epilepsy)

Research Description:

Our laboratory studies the biology of protein growth factors in the brain, with a special interest in proteins with the potential to mediate pathological interactions between the nervous, immune, and vascular systems in neurological disease. Our current diseases of most interest are epilepsy, dementia, and neurally-mediated autoimmune disease.

Selected Publications:

    Nicoletti J.N., Shah, S.K., Goodman J.H., McCloskey, D., Elkady A., Khalid, S., Hylton D.A., Rudge J.S., Scharfman, H.E., & Croll S.D. (2008). Vascular endothelial growth factor (VEGF) is upregulated after status epilepticus and serves a neuroprotective role. Neuroscience, 151(1):232-241.

    Kasselman L.J., Kintner J., Sideris A., Pasnikowski E., Krellman J.W., Shah S., Rudge J.S., Yancopoulos G.D., Wiegand S.J., & Croll S.D. (2007). Dexamethasone Treatment and ICAM-1 Deficiency Impair VEGF-Induced Angiogenesis in Adult Brain. The Journal of Vascular Research, 44(4):283-291.

    Kasselman L.J., Sideris A., Bruno C., Perez W.R., Cai N., Nicoletti J.N., Wiegand S.J., & Croll S.D. (2006). BDNF: A missing link between sympathetic dysfunction and inflammatory disease? The Journal of Neuroimmunology, 175(1-2):118-127.

    McCloskey D.P., Croll, S.D., & Scharfman H.E. (2005) Vascular endothelial growth factor (VEGF) decreases in vitro hippocampal glutamatergic excitability. The Journal of Neuroscience, 25(39):8889-8897.

    Scharfman H.E., Goodman J.H., MacLeod A., Phani S., Antonelli C., & Croll S.D. (2005) Increased neurogenesis and ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental Neurology, 192(2), 348-356.

    Croll, S.D., McCloskey, D.P., Nicoletti, J.N. & Scharfman, H.E. (2005) VEGF as a seizure therapeutic: Killing Two Birds with One Stone. In D.K. Binder & H.E. Scharfman (Eds.), Growth Factors and Epilepsy, Nova Sciences: New York.

    Scharfman H.E., Goodman J.H., MacLeod A., Phani S., Antonelli C. & Croll S.D. (2005) Increased neurogenesis and ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental Neurology, 192(2):348-56.

    Barnea, A., Roberts, J. & Croll, S.D. (2004) Continuous exposure to brain-derived neurotrophic factor (BDNF) is required for persistent activation of TrkB receptor, the ERK signaling pathway, and the induction of neuropeptide Y (NPY) production. Brain Research 1020 (1-2):106-117.

    Croll, S.D., Ransohoff, R.M., Cai, N., Zhang, Q., Martin, F.J., Wei, T., Kasselman, L.J., Kintner, J., Murphy, A.J., Yancopoulos, G.D. & Wiegand, S.J. (2004) VEGF-mediated inflammation precedes angiogenesis in adult brain. Experimental Neurology, 187(2):388-402.

    Croll, S.D., Goodman, J.H., & Scharfman, H.E. (2004) VEGF in Epilepsy: A Double-Edged Sword? In Molecular Mechanisms of Epileptogenesis, Scharfman, H.E. and Binder, D.K., Eds., Landes Bioscience.

    Scharfman, H.E., Goodman, J.H., Sollas, A.L., & Croll, S.D. (2002) Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor (BDNF). Experimental Neurology, 174, 201-214.

    Croll, S.D. & Wiegand, S.J. (2001) Vascular growth factors in cerebral ischemia. Molecular Neurobiology, 23(2/3), 121-135.

    Binder, D.K., Croll, S.D., Gall, C.M. & Scharfman, H.E. (2001) BDNF and epilepsy: Too much of a good thing? Trends in Neurosciences, 24(1), 47-53.